"Inkwell" valvoplasty (five dogs) and Nissen gastropexy (five dogs) were performed following esophagogastrectomy and compared with simple esophagogastrostomy (five dogs). The two valvoplasties were effective in preventing reflux esophagitis and anastomotic leak, which was confirmed by postoperative fluoroscopy, esophagoscopy, in vivo and in vitro mechanical reflex pressure measurements, and autopsy. With inkwell valvoplasty the capacity to vomit was retained, and web-like strictures at the anastomotic line were easily dilated. The Nissen gastric plication developed a stricture which was much more difficult to dilate.