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pmid: 2818244
To the Editor. —We would like to comment on the article by Johnson et al 1 that appeared in the April 1988 issue of theArchives. 1 The authors reported that single photon emission computed tomography (SPECT) brain imaging with iofetamine hydrochloride I 123 was able to reflect dementia severity in patients with Alzheimer's disease (AD). To determine dementia severity, they used a global estimate of functional disability on a 4-point scale. Dividing a group of patients with AD into several groups based on functional impairment seems rather artificial. The great range of overlap in score on the Blessed Dementia Scale 2 between the four groups (Table 1 in the article) seems to support this. In our opinion, a comparison of the whole spectrum of dementia should be made with SPECT abnormalities. Further-more, dementia severity was determined by estimating functional disability, without referring to previous ability. We think that the
Tomography, Emission-Computed, Single-Photon, Alzheimer Disease, Brain, Humans
Tomography, Emission-Computed, Single-Photon, Alzheimer Disease, Brain, Humans
citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | 17 | |
popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network. | Average | |
influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | Top 10% | |
impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network. | Top 10% |