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Oral Crystalline Cyanocobalamin Available

Authors: Vincent Lacroce;

Oral Crystalline Cyanocobalamin Available

Abstract

To the Editor. —I read an article in the DecemberArchives(1980;140:1582) concerning the use of liquid cyanocobalamin marketed for intramuscular use. According to Crosby, the injectable cyanocobalamin was used because of the unavailability of an oral form of cyanocobalamin. He claimed it would be wise "if the FDA [Food and Drug Administration] would authorize the marketing of cobalamin for oral therapy of pernicious anemia." I have written to inform Crosby that there is an oral crystalline cyanocobalamin available for use in pernicious anemia. It is marketed by the Merck Sharp & Dohme Co under the trade name Redisol (strength, 500 μg). It is marketed also by various generic manufacturers in 1,000- and 500-μg strengths; 1,000 μg daily of any of these products would probably have maintained this patient's condition in remission. If possible, I would like to know why Crosby did not use this product in this case.

Keywords

Vitamin B 12, Anemia, Pernicious, Administration, Oral, Humans

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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
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Average
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