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Parathyroid Gland Metabolism

Name: Parathyroid Gland Metabolism
Creator: Lawrence G. Raisz
Keywords: Calcitonin, Ions, Time Factors, Acute Kidney Injury, Hydrogen-Ion Concentration, Phosphates, Rats, 3. Good health, Parathyroid Glands, Fluorides

descriptionPublicationkeyboard_double_arrow_right Article 01 Oct 1969 English Publisher:American Medical Association (AMA)Journal:Archives of Internal Medicine, volume 124, page 389 (issn: 0003-9926,

Authors: Lawrence G. Raisz;

doi: 10.1001/archinte.1969.00300200001001

pmid: 4898544

Parathyroid Gland Metabolism

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Abstract

The parathyroids differ from other endocrine glands in several respects. (1) The parathyroids appear late in phylogeny, being seen first in the amphibia. (2) While most endocrine glands make more than one hormone, only one hormone and one secretory cell type are regularly found in the parathyroids. (3) While most endocrine glands are under complex control involving both long and short feedback loops, the parathyroid glands have a unique feedback control by the concentration of divalent cations in the blood. Of course, indirect effects on parathyroid function can occur which act via changes in divalent cation concentration, so that the complexity of parathyroid control may be as great as that of other endocrines. The physiologic role of the parathyroid glands is to regulate serum ionized calcium concentration. However, changes in the concentration of both magnesium and calcium ions can affect parathyroid function. The chief reason that the parathyroids regulate

Keywords

Calcitonin, Ions, Time Factors, Acute Kidney Injury, Hydrogen-Ion Concentration, Phosphates, Rats, Parathyroid Glands, Fluorides, Calcification, Physiologic, Dogs, Parathyroid Hormone, Protein Biosynthesis, Animals, Kidney Failure, Chronic, Calcium, Cattle, Magnesium, Amino Acids, Vitamin D

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	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Top 10%
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Top 10%