Human nail infections due to members of the genus Microsporum are not often encountered (M. audouini,1M. canis,2,3and M. gypseum4,5). Since to our knowledge nail infection by M. gypseum has not yet been described in the American literature, the following case report may be of interest. A white female teacher aged 34 years was first seen on Oct. 12, 1957. She complained of nail changes which appeared six weeks prior to her first visit, involving the right ring and middle fingers and the left ring finger. Examination revealed the following: The distal portion of the left ring fingernail showed disintegration, thinning, and scaling. The distal portions of the right ring and right middle fingernails were absent. The exposed nail beds were covered with scales. All three of these fingernails presented a grayish brown discoloration. Microscopic examination of combined scrapings from the involved nails showed