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Cytodiagnosis of Cutaneous Malignancy

Authors: Frederick Urbach; Eugene M. Burke; Herbert L. Traenkle;

Cytodiagnosis of Cutaneous Malignancy

Abstract

Cytologic methods for the diagnosis of cancer have been utilized in various ways at least since 1867. 1 Since 1943, when Papanicolaou and Traut wrote a monograph on exfoliative cytology, modifications of their method have been applied to most body areas where secretions or exudates can be obtained. In almost all of these situations, the materials examined have been exfoliated cells. Individual cell morphology rather than tissue structure has been used as diagnostic criterion. Cutaneous tumors do not lend themselves readily to the study of exfoliated cells, since their surfaces are either intact, hyperkeratotic, or crusted. Several methods for obtaining smears from skin tumors have been reported, varying from impression smears and aspiration (needle) biopsy 2 to superficial curette abrasion. 3 Wright stain, May-Grunwald-Giemsa, and various Papanicolaou modifications have been used for staining. 4 Large-scale studies of the application of cytodiagnostic techniques to skin

Keywords

Skin Neoplasms, Cytodiagnosis, Humans

  • BIP!
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    citations
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    15
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Average
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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Found an issue? Give us feedback
citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
15
Average
Top 10%
Average
Related to Research communities
Cancer Research
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