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The modern approach to intravesical therapy of chronic cystitis

The modern approach to intravesical therapy of chronic cystitis

Abstract

Трудности лечения больных с хроническим рецидивирующим циститом обусловлены как различными факторами вирулентности уропатогенной кишечной палочки, так и состоянием локальной резистентности слизистой оболочки мочевого пузыря и их взаимодействием. Применение инстилляций Инстилана в комплексной терапии больных с хроническим циститом привело к выраженной положительной клинической динамике у 95% пациентов, а также к снижению количества рецидивов цистита более чем в 2 раза, что существенно улучшило качество жизни больных. Полученные результаты позволяют рекомендовать применение гиалуроната натрия для внутрипузырной терапии различных форм хронического цистита.

The difficult of treating patients with chronic recurrent cystitis are caused by various factors like virulence of uropathogenic Escherichia coli, and the state of the local resistance of the bladder mucosa and their interaction. Instilan instillations in the treatment of patients with chronic cystitis led to a pronounced positive dynamics of clini cal 95% of patients, as well as to reduce the number of recurrences of cystitis more than 2 times, which greatly improved the quality of life of patients. The results allow us to recommend the use of intravesical sodium hyaluronate for the treatment of various forms of chronic cystitis.

Труднощі лікування хворих з хронічним рецидивуючим циститом зумовлені як різними факторами вірулентності уропатогенної кишкової палички, так і станом локальної резистентності слизової оболонки сечового міхура і їх взаємодією. Застосування інстиляцій Інстілану в комплексній терапії хворих на хронічний цистит призвело до вираженої позитивної клінічної динаміки у 95% пацієнтів, а також до зниження кількості рецидивів циститу більш ніж в 2 рази, що істотно поліпшило якість життя хворих. Отримані результати дозволяють рекомендувати застосування гіалуронату натрію для внутрішньоміхурової терапії різних форм хронічного циститу.

Keywords

chronic cystitis; intravesical therapy; instilan, хронический цистит; интравезикальная терапия; Инстилан, УДК 616.62-002.2:615.032.62, хронічний цистит; інтравезикальна терапія; Інстілан

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
gold