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MICROTÚBULOS Y TERAPIA NEURAL: PROPUESTA DE UNA INVESTIGACIÓN PROMISORIA

Authors: CRUZ, YAMILE; FAYAD, RAMÓN;

MICROTÚBULOS Y TERAPIA NEURAL: PROPUESTA DE UNA INVESTIGACIÓN PROMISORIA

Abstract

La terapia neural es una práctica médica no convencional en la cual se inyectan anestésicos locales (procaÃna o lidocaÃna) en concentraciones en un rango de 1 - 10 mg/ml, en cantidades entre 1-10 cm3, en diferentes partes del cuerpo con fines terapéuticos mas no anestésicos. El mecanismo de acción de los anestésicos locales en esta terapia no se conoce. La posible acción remota de la procaÃna, el efecto de sus propiedades eléctricas en el transporte de señales en el sistema nervioso y en el restablecimiento del potencial fisiológico de membrana son temas centrales de la terapia neural que requieren una interpretación fÃsico-quÃmica. En este artÃculo proponemos que la propagación de señales en microtúbulos neuronales podrÃa estar involucrada en los mecanismos de acción de la procaÃna en terapia neural. Sugerimos algunos estudios experimentales que conduzcan a una interpretación cientÃfica rigurosa de las observaciones reportadas y de los efectos remotos que se atribuyen a la inyección de procaÃna en terapia neural. Neural therapy is a non-conventional medical practice in which the injection of local anesthetics (procaine and lidocaine) in concentrations in the range of 1 - 10 mg/ml, in quantities between 1-10 cm3 , is applied in different parts of the body with therapeutical but not anesthetics purposes. The mechanism of action of local anesthetics in this therapy is not known. The possible remote action and the electrical effect of procaine on the signal transport and on the membrane is normal potential recovery are very important issues in neural therapy, and a physico-chemical explanation of these phenomena is required. In this paper we propose that the propagation of signals in neural microtubules could be involved in the mechanism of action of procaine in neural therapy. We suggest some experimental studies in order to find a more rigorous scientific interpretation of the reported observations and of the remote effects that are assigned to the injection of procaine in neural therapy. A terapia neural é uma prática médica não convencional em que se injetam anestésicos locais (procaÃna ou lidocaÃna) em concentrações variando de 1 a 10 mg / ml, em quantidades 1-10 cm3, em diferentes partes do corpo para fins terapêuticos, mas não anestésicos. O mecanismo de ação dos anestésicos locais nesta terapia não é conhecido. O possÃvel ação remota da procaÃna, o efeito das propriedades elétricas no transporte de sinais no sistema nervoso e restabelecimento do potencial fisiológico de membrana são os temas centrais da terapia neural que requerem uma interpretação fÃsico quÃmica. Neste artigo propomos que a propagação de sinais em microtúbulos neuronais poderiam estar envolvidos nos mecanismos de ação da procaÃna na terapia neural. Se sugerem estudos experimentais que levam a uma interpretação cientÃfica rigorosa das observações relatadas e dos efeitos remotos que são atribuÃdas à injeção de procaÃna na terapia neural.

Keywords

microtubules, neural therapy, microtúbulos, procaÃna, electrical permitivity, procaine, permissividade elétrica, permitividad eléctrica, terapia neural

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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
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