This paper presents the analysis of truck platoon dynamics using a simulation environment. In this case the platoon consists of a number of trucks following each other using driver algorithms. MADYMO (a multibody and FE software package) and MATLAB/SIMULINK are coupled to allow for these driver algorithms to act on the detailed multibody vehicle models. Using this concept, the longitudinal dynamics of a truck platoon are investigated. The individual trucks are controlled by an Adaptive Cruise Control algorithm. It is aimed for to make the platoon dynamics robust for different vehicle configurations such as size, payload, brake system dynamics and tyre behaviour. The results show that the combined MATLAB/MADYMO environment is well suited for conducting these design and analysis studies.