In recent years, Florence has been affected by an increasing number of initiatives that focus their planning and care practices on spaces that are often abandoned and underused, catalysing new relationships between different actors with the aim of identifying and promoting new uses that can respond more effectively to the social challenges imposed by the contemporary world. Even if the overall balance of these practices is still weak in terms of effective change in the way of producing economically, ecologically and environmentally more sustainable cities and territories, realities are emerging, such as Spazio Lumen, investigated in this contribution, which present traces of possible ways to proceed in this direction. Through the reading and analysis of this experience, the contribution draws a brief portrait of its strengths and hopes for some future trajectories.