The Orinoco Oil Belt (OOB) as a principal oil reservoir in the world mark a milestone in new technologies and innovation, this situation let us affront all inherent challenges and improve the productivity in this important zone. The study was designed in order to asset increase in the production levels for horizontal wells, this specific type of wells represent most important support of production in Petro San Félix company operations. However, they are suffering an important reduction of production for natural declining factors and damage at liner face or well down area. The methodology was based in a selection of better candidates under technical and economic considerations, these opportunities was included in the evaluation matrix, measured and compared to rank best options to work. In each case, geological properties and dynamics flow in the well was determining in the kind of treatment to use. The methodology has been reviewed with statistical results in order to include this feedback and improve it with the state of art. Results for this procedure include 80 candidates wells basket. After 7 months activities, have been worked 38 wells and production increase of 1812 barrels per day. Methodology could be used as model in other areas around Orinoco Oil Belt, because the applicability and economics was demonstrated in the Petro San Félix simple used for this study.