
Present article discusses the possible risk factors of gestosis development. As the result of present research it was discovered that the cause of gestosis development is polymorphism с.582-353-379 del in the gene of endothelial NO-synthase. Burdened heredity in the form of arterial hypertension, gestosis, stroke, cardiac infarction, diabetes mellitus are the risk factors of gestosis development. Gestosis prediction can be done before pregnancy, on the condition of heredity research and genetic typing.
В статье рассматриваются возможные факторы риска развития гестоза. В результате данного исследования выявлена ассоциация развития гестоза с полиморфизмом с.582-353-379 del в гене эндотелиальной NO-синтазы. Отягощенная наследственность в виде артериальной гипертензии, гестоза, инсульта, инфаркта миокарда, сахарного диабета является фактором риска развития гестоза. Прогнозирование гестоза возможно до беременности, при условии изучения наследственности и проведения генотипирования.
ГЕСТОЗ, ЭНДОТЕЛИАЛЬНАЯ NO-СИНТАЗА, НАСЛЕДСТВЕННАЯ ПРЕДРАСПОЛОЖЕННОСТЬ
ГЕСТОЗ, ЭНДОТЕЛИАЛЬНАЯ NO-СИНТАЗА, НАСЛЕДСТВЕННАЯ ПРЕДРАСПОЛОЖЕННОСТЬ
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