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Влияние терапии гипохлоритом натрия на перекисное окисление липидов, антиоксидантную защиту, цитолитический и мезенхимально-воспалительный синдромы у больных токсическими гепатитами

Влияние терапии гипохлоритом натрия на перекисное окисление липидов, антиоксидантную защиту, цитолитический и мезенхимально-воспалительный синдромы у больных токсическими гепатитами

Abstract

У 106 пациентов токсическими гепатитами проводилось лечение курсом внутривенных капельных инфузий растворов гипохлорита натрия в виде монотерапии. До и после курса лечения у больных исследовались уровни перекисного окисления липидов, ферменты антиоксидантной защиты, показатели цитолитического и мезенхимально-воспалительного синдромов. После терапии выявлена значительная позитивная динамика всех показателей, а также улучшение субъективного состояния пациентов. Таким образом, лечение гипохлоритом натрия является эффективным методом медикаментозной терапии у больных с токсическими гепатитами.

106 patients with toxic hepatitis were treated with the infusion course of sodium hypochlorite as monotherapy. Levels of lipid peroxidation, antioxidative enzymes activity, cytolytic and mesenchimal-inflammatory syndrome were determined before and after therapy course. Treatment revealed valuable positive dynamics of all indexes, improvement of the general status of patients after therapy. Thus, treatment with sodium hypochlorite is a new effective medicamentous method in patients with toxic hepatitis.

Keywords

ГИПОХЛОРИТ НАТРИЯ, ПЕРЕКИСНОЕ ОКИСЛЕНИЕ ЛИПИДОВ, АНТИОКСИДАНТНАЯ ЗАЩИТА, ЦИТОЛИТИЧЕСКИЙ СИНДРОМ, МЕЗЕНХИМАЛЬНО-ВОСПАЛИТЕЛЬНЫЙ СИНДРОМ, ТОКСИЧЕСКИЙ ГЕПАТИТ

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
gold