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Диагностическое значение определения мозгового натрийуретического пропептида у больных геморрагической лихорадкой с почечным синдромом

Диагностическое значение определения мозгового натрийуретического пропептида у больных геморрагической лихорадкой с почечным синдромом

Abstract

The study of content of cerebral natriuretic propeptide (NT-proBNP) in patients with hemorrhagic fever and renal syndrome was carried out considering severity degree, period of disease, presence of clinical roentgenological signs of lungs af-fection. It is demonstrated that in patients with mild and severe degree of disease the content of NT-proBNP is reliably higher than in the control group and gets its peak values in oliguric period. The indices of NT-proBNP are reliably higher in patients with clinical roentgenological signs of lungs affection as compared with patients without such signs. The correlation analysis revealed direct dependence between the content of NT-proBNP and systolic blood pressure in pulmonary ar-tery in in patients with hemorrhagic fever and renal syndrome of mild severity.

Проведено исследование содержания мозгового натрийуретического пропептида (NT-proBNP) у больных геморрагической лихорадкой с почечным синдромом (ГЛПС) в зависимости от степени тяжести, периода заболевания, наличия клинико-рентгенологических признаков поражения легких. Показано, что у больных со средней и тяжелой формой заболевания уровень NT-proBNP достоверно выше, чем в контрольной группе, и достигает максимума в олигурический период. Показатели NT-proBNP достоверно выше у больных с наличием клинико-рентгенологических признаков поражения легких в сравнении с больными без таких признаков. Корреляционный анализ выявил прямую зависимость между уровнем NT-proBNP и систолическим давлением в легочной артерии (СДЛА), у больных со среднетяжелой формой ГЛПС.

Keywords

ГЕМОРРАГИЧЕСКАЯ ЛИХОРАДКА С ПОЧЕЧНЫМ СИНДРОМОМ, ЛАБОРАТОРНАЯ ДИАГНОСТИКА, МОЗГОВОЙ НАТРИЙУРЕТИЧЕСКИЙ ПРОПЕПТИД

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
gold