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Изменения метаболизма в лимфоцитах при гриппе

Изменения метаболизма в лимфоцитах при гриппе

Abstract

Aim. To assess the nature and intensity of metabolic processes in lymphocytes of patients with influenza according to the activity of intracellular enzymes in comparison to the severity of the disease. Methods. Determined were the enzymatic parameters of lymphocytes of 45 patients aged 18 to 42 years with a diagnosis of «influenza». Two groups of patients were formed: with moderate (24 patients) and severe (21 patients) course of the disease. Used as controls were the values the activity of intracellular enzymes of lymphocytes of 37 practically healthy individuals of comparable age. Results. In patients with a moderately severe course of the influenza compared with the controls noted was a significant increase in activity of glucose-6-phosphate dehydrogenase (3.17±0.53 and 2.74±0.31 mkE/10 000 cells, p

Цель. Оценка характера и интенсивности метаболических процессов в лимфоцитах больных гриппом по изменениям активности внутриклеточных ферментов в сопоставлении с тяжестью течения болезни. Методы. Определяли энзиматические показатели лимфоцитов 45 больных в возрасте от 18 до 42 лет с диагнозом «грипп». Выделено две группы больных: со среднетяжёлым (24 пациента) и тяжёлым (21 пациент) течением заболевания. В качестве контрольных показателей использовали значения активности внутриклеточных ферментов лимфоцитов 37 практически здоровых людей сопоставимого возраста. Результаты. У больных со среднетяжёлым течением гриппа по сравнению с контролем отмечено достоверное повышение активности глюкозо-6-фосфатдегидрогеназы (3,17±0,53 и 2,74±0,31 мкЕ/10 000 кл., р

Keywords

ГРИПП, ЛИМФОЦИТЫ, МЕТАБОЛИЧЕСКИЕ ПРОЦЕССЫ, АКТИВНОСТЬ ВНУТРИКЛЕТОЧНЫХ ФЕРМЕНТОВ

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
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