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Возможности ранней диагностики цервикальной недостаточности для профилактики сверхранних преждевременных родов

Возможности ранней диагностики цервикальной недостаточности для профилактики сверхранних преждевременных родов

Abstract

This paper presents the efficiency estimation of early diagnosis of cervical failure (CF) and its correction in pregnant women without clinical symptoms for preventing extremely premature delivery. We examined 277 pregnant women without clinical symptoms of premature delivery, with the cervical canal length of <25 mm, which were divided into groups according to their gestation period: 14 +0-17 +6, 18 +0-21 +6, and 22 +0-24 +6 weeks. It is established that women with the cervical canal length of < 25 mm in 14 +0-17 +6 weeks of pregnancy have greater risk of spontaneous abortion than the same in 18 +0-21 +6 weeks. In 115 cases some tests were made to detect the presence of placental alpha microglobulin-1 (PAMG-1). Detection of PAMG-1 in 14 +0-21 +6 weeks gestation provides very important information about fetal viability. For CF correction we used an obstetric pessary and McDonald cerclage. Termination of pregnancy before 22 nd week and delivery after 22 +0-27 +6 weeks were taken as a general outcome.

В статье дана оценка эффективности ранней диагностики цервикальной недостаточности и ее коррекции у беременных без клинических симптомов для профилактики сверхранних преждевременных родов. Обследовано 277 беременных без клинических симптомов преждевременных родов с длиной цервикального канала <25 мм, разделенных на группы в зависимости от гестационного возраста на момент выявления: 14 +0-17 +6, в 18 +0-21 +6 и 22 +0-24 +6. Установлено, что женщины с длиной цервикального канала <25 мм в 14 +0-17 +6 недель беременности имеют более высокий риск самопроизвольного аборта, чем те, у кого это выявилось в 18 +0-21 +6. В 115 случаях выявляли плацентарный альфа микро-глобулин-1 (ПАМГ-1). Определение ПАМГ-1 в сроке гестации 14 +0-21 +6 дает важную информацию о перспективах получения жизнеспособного плода. Для коррекции цервикальной недостаточности применялись акушерский пессарий и наложение швов по Макдональду. Основным исходом считали прерывание беременности до 22 недель и роды в сроке 22+0-27+6 недель.

Keywords

ЦЕРВИКАЛЬНАЯ НЕДОСТАТОЧНОСТЬ, ПАМГ-1, СВЕРХРАННИЕ ПРЕЖДЕВРЕМЕННЫЕ РОДЫ, ХИРУРГИЧЕСКИЙ СЕРКЛЯЖ, АКУШЕРСКИЙ СЕРКЛЯЖНЫЙ ПЕССАРИЙ

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
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