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Влияние производного индола SS-68 на коронарное кровообращение, сократительную активность сердца и общую гемодинамику в условиях интактного миокарда

Влияние производного индола SS-68 на коронарное кровообращение, сократительную активность сердца и общую гемодинамику в условиях интактного миокарда

Abstract

Исследовано влияние производного индола SS -68 на коронарное кровообращение, сократительную активность сердца и общую гемодинамику в условиях интактного миокарда в опытах на крысах, кошках и собаках. Установлено, что SS-68 дозозависимо повышает объемную скорость коронарного кровотока, создает в миокарде дополнительный кислородный резерв, снижает артериальное давление и, в меньшей мере, сократимость миокарда, урежает частоту сердечных сокращений.

The effect of indole derivatives SS-68 on the coronary circulation, the contractile activity of the heart and systemic hemodynamic in the intact myocardium in rats, cats and dogs has been studied. It has been found that the SS-68 dose-dependently increases the volume rate of coronary blood flow, creates additional oxygen reserve in the myocardium, lowers blood pressure and, to a lesser extent, myocardial contractility, slows the heart rate.

Keywords

ПРОИЗВОДНОЕ ИНДОЛА SS-68, КОРОНАРНОЕ КРОВООБРАЩЕНИЕ, СОКРАТИМОСТЬ МИОКАРДА, ОБЩАЯ ГЕМОДИНАМИКА, ИНТАКТНЫЙ МИОКАРД

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
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