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Методика высокодозной гипофракционной стереотаксической лучевой терапии для злокачественных опухолей легкого

Методика высокодозной гипофракционной стереотаксической лучевой терапии для злокачественных опухолей легкого

Abstract

Рассмотрена технология высокодозной стереотаксической лучевой терапии у больных злокачественными опухолями легкого при использовании системы активного контроля дыхания методикой УМАТ. Были пролечены 26 больных с диагнозом «немелкоклеточный рак легкого» и единичными метастазами в легкое. Проведение лучевой терапии осуществлялось на стереотаксическом линейном ускорителе. Показано, что высокодозная гипофракционная стереотаксическая лучевая терапия является безопасным методом для лечения начальных опухолей легкого и единичных метастазов в легкое, позволяет эффективно осуществлять локальный контроль над опухолью и быть альтернативой хирургическому лечению у неоперабельных больных.

Hypofractionated stereotactic radiotherapy was used for 26 patients at medically inoperable stage I of non-small cell lung cancer with dose escalation of 48-54 Gy prescribed at 90 or 95% isodose level in 3-4 fractions. Nine-months local control and cancer-specific survival were 82.0 and 66.8% respectively, with minimal toxicity. For metastatic lung tumors local control was obtained in 92% cases. Hypofractionated stereotactic radiation therapy (SBRT) is safe and feasible for the treatment of inoperable primary lung cancer and single lung metastasis.

Keywords

СТЕРЕОТАКСИЧЕСКАЯ КОНФОРМНАЯ ЛУЧЕВАЯ ТЕРАПИЯ, ГИПОФРАКЦИОНИРОВАНИЕ, РАДИОТОКСИЧНОСТЬ, РАДИОХИРУРГИЯ

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
gold
Related to Research communities
Cancer Research