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Отдаленные результаты хирургического лечения при папиллярном раке щитовидной железы и сравнительная оценка тактики лечения

Отдаленные результаты хирургического лечения при папиллярном раке щитовидной железы и сравнительная оценка тактики лечения

Abstract

Дифференцированные карциномы щитовидной железы в плане прогноза по-разному оцениваются в европейских, японских и американских тиреоидных рекомендациях, что отражается в различных подходах к их лечению. Материал и методы. Мы проанализировали данные 331 пациента с папиллярными карциномами щитовидной железы, прооперированных в период с 1966 по 2000 г. Средний срок наблюдения за больными составил 18,8 лет, наибольший срок наблюдения 57 лет.Результаты. Анализ выживаемости пациентов после операции подтвердил благоприятное течение заболевания с учетом того, что в те годы отсутствовали сонография и тонкоигольная биопсия и пациенты оперировались в основном на более поздних стадиях опухолевого процесса. Наиболее значимыми в плане прогноза являются размер опухоли на момент оперативного вмешательства, наличие отдаленных метастазов. Отдаленные результаты оперативного лечения практически не зависят от его характера (полное или частичное удаление органа, выполнение или невыполнение профилактической лимфодиссекции). Смертность и количество рецидивов у пациентов, не прошедших лечение радиоактивным йодом, существенно не отличаются от данных литературы.

There are discriminating approaches towards differentiated thyroid carcinomas due to their different prognoses according to the European, American and Japanese thyroid recommendations. Materials and Methods. We have analyzed data on 331 patients with papillary thyroid cancer, operated on during the period of 1966-2000 years. Mean observation period was 18.8 years, the maximum period of observation was 57 years.Results. Survival rate analysis after surgical treatment showed favourable prognosis for thyroid cancer patients, adjusted for that there was no ultrasonography and FNAB during those years, and patients had generally more progressive tumours. One of the most important factors for the prognosis of a patient is the size of a tumour at the moment of operation and presence of distant metastases. Long-term results of surgical treatment are practically independent of its extent (thyroidectomy or thyroid resection, prophylactic lymphodissection). Mortality and recurrence rates in patients who were not submitted to radioactive iodine treatment do not differ considerably from literature data.

Keywords

ПАПИЛЛЯРНАЯ КАРЦИНОМА ЩИТОВИДНОЙ ЖЕЛЕЗЫ, ХИРУРГИЧЕСКОЕ ЛЕЧЕНИЕ, ОТДАЛЕННЫЕ РЕЗУЛЬТАТЫ ЛЕЧЕНИЯ

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
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