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Иммуноморфологические корреляты противоопухолевого влияния низкоинтенсивных электромагнитных воздействий в эксперименте

Иммуноморфологические корреляты противоопухолевого влияния низкоинтенсивных электромагнитных воздействий в эксперименте

Abstract

For the first time quantitative changes in tumor tissue and immune cells infiltration caused by effective electromagnetic factors of low intensity were described in experiments on rats with sarcoma 45. Special antitumor agents were not applied. The factors included radiation of extra high frequency and radiation of infra low frequency or SСENAR-therapy. The combined factors were applied in accordance with the regimes of the activation therapy aimed to development of the antistress adaptation reactions and to achievement of expressed antitumor effect. Marked antitumor effect manifested in the inhibition of growth (over 70 %) or tumor regression (by 60–100 %) in most animals. Obtained results indicate to immune effector mechanisms of systemic antitumor effect of the combined electromagnetic factors.

Впервые описаны количественные изменения в ткани экспериментальных опухолей и составе инфильтрирующих опухоль клеток иммунной системы при эффективных электромагнитных воздействиях без применения специальных противоопухолевых средств. В экспериментах на белых беспородных крысах с саркомой 45 использовали слабые излучения крайне высокочастотного и инфра низкочастотного диапазона, а также СКЭНАР-терапию. Воздействия применяли с локализацией на структуры ЦНС, в режимах активационной терапии. Противоопухолевый эффект заключался в торможении роста опухоли на 71-73 % или регрессии опухоли на 60–100 %. Полученные результаты указывают на иммунный механизм повреждения ткани опухоли под влиянием исследованных электромагнитных воздействий.

Keywords

ЭЛЕКТРОМАГНИТНЫЕ ВОЗДЕЙСТВИЯ, ПРОТИВООПУХОЛЕВЫЙ ЭФФЕКТ, АНТИСТРЕССОРНЫЕ АДАПТАЦИОННЫЕ РЕАКЦИИ, КЛЕТКИ ИММУННОЙ СИСТЕМЫ, ИНФИЛЬТРАЦИЯ ОПУХОЛИ

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
gold