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Прогнозирование ранней и поздней инвалидизации пациентов с паркинсонизмом с использованием факторного анализа

Прогнозирование ранней и поздней инвалидизации пациентов с паркинсонизмом с использованием факторного анализа

Abstract

В ходе факторного анализа 28 показателей, характеризующих особенности клинического течения, качество жизни и состояние психики у 94 больных с паркинсонизмом, установлено, что строгим критерием, определяющим раннюю или позднюю инвалидизацию, является время дебюта болезни. Манифестация данного заболевания в относительно молодом возрасте является прогностическим благоприятным фактором, т.к. стойкая утрата трудоспособности в таком случае развивается спустя довольно продолжительный промежуток времени. У больных более старшего возраста инвалидизация после дебюта болезни наступает гораздо быстрее. Как при первичном, так и при вторичном паркинсонизме наблюдается значительное снижение качества жизни, особенно у больных с ранней инвалидизацией, сочетающейся с деменцией и тревожно-депрессивными расстройствами.

In the factor analysis of 28 parameters that characterize the clinical features, quality of life and mental state in 94 patients with Parkinson's disease, it was found that the strict criteria that determines early or late disability is the disease onset time. Manifestation of this disease at a relatively young age is a predictive favourable factor, since persistent disability develops after a fairly long period of time in such case. Older patients become disabled much faster after the disease onset. Both primary and secondary parkinsonism exhibit a significant reduction in the quality of life, especially in case of patients with early disability, coupled with dementia and anxiodepressive disorders.

Keywords

ПАРКИНСОНИЗМ, РАННЯЯ ИНВАЛИДИЗАЦИЯ, ПОЗДНЯЯ ИНВАЛИДИЗАЦИЯ, МНОГОФАКТОРНЫЙ СТАТИСТИЧЕСКИЙ АНАЛИЗ

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
bronze