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Клиническое значение исследования пневмопротеинов у глубоко недоношенных детей

Клиническое значение исследования пневмопротеинов у глубоко недоношенных детей

Abstract

Представлены данные об изменениях содержания сурфактантного протеина D и белка клеток Клара в крови и лаважной жидкости у 106 новорожденных детей гестационного возраста 26-32 нед массой тела при рождении 660-1500 г, имеющих дыхательные расстройства. Установлено, что концентрации этих белков в бронхоальвеолярной жидкости и сыворотке крови были существенно увеличены у больных с врожденной пневмонией по сравнению с их содержанием у детей с респираторным дистресс-синдромом (РДС). Низкое содержание сурфактантного протеина D и белка клеток Клара у недоношенных новорожденных с РДС было связано с последующим развитием бронхолегочной дисплазии.

The data on changes in the surfactant protein D and Clara cell protein content in the blood and alveolar lavage fluid in 106 infants born at 26-32 weeks of gestation with birth weight of 660-1500 g suffered from respiratory disorders are presented. In patients with congenital pneumonia concentrations of these proteins in broncho-alveolar fluid and serum levels were found to be significantly higher than in infants with respiratory distress syndrome (RDS). The low content of surfactant protein D and Clara cell protein in premature infants with RDS was associated with the subsequent development of bronchopulmonary dysplasia.

Keywords

ГЛУБОКОНЕДОНОШЕННЫЕ ДЕТИ, ДЫХАТЕЛЬНЫЕ РАССТРОЙСТВА, СУРФАКТАНТНЫЙ ПРОТЕИН D, БЕЛОК КЛЕТОК КЛАРА

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
gold