
A case of the longstandindg microfilaraemia due to Dirofilaria repens is presented as a 57-years-old female. This is the first report of the longstandindg microfilaraemia in a Russian patient due to infection of D. repens. The microfilariae of D. repens were detected due to multiple investigations of fresh drops of blood. The longstandindg microfilaraemia due to D. repens is discussed regarding their role in human pathology. As the larvae mature into adult wormes they migrate through blood vessels and the subdermal connective tissues causing pruritis, oedematous lesions on the skin, itching and pain as they pass beneath the conjunctivae and penetrate internal organs. The patient was successfully treated with doxycycline, albendazole and diethylcarbamazine.
Описан случай инвазии Dirofilaria repens у больной с неспецифической клинической симптоматикой, заразившейся в Московской области. В препаратах периферической крови больной были обнаружены личинки дирофилярий, которые выявлялись в течение двух месяцев. Данное наблюдение способствовало открытию пути миграции гельминта по кровеносным сосудам в организме человека и пути инвазирования внутренних органов, а также показало способность половозрелых дирофилярий спариваться и продуцировать личинки микрофилярии. Показана эффективность комбинированной терапии дирофиляриоза repens с использованием доксициклина, албендазола и диэтилкарбамазина. Отмечается объективная сложность диагностики дирофиляриоза repens и обсуждаются проблемы лечения.
МИКРОФИЛЯРИЕМИЯ D. REPENS, ЭНДОСИМБИОНТ WOLBACHIА, ДОКСИЦИКЛИН, АЛБЕНДАЗОЛ, ДИЭТИЛКАРБАМАЗИН
МИКРОФИЛЯРИЕМИЯ D. REPENS, ЭНДОСИМБИОНТ WOLBACHIА, ДОКСИЦИКЛИН, АЛБЕНДАЗОЛ, ДИЭТИЛКАРБАМАЗИН
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