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Первый в России аутохтонный случай выявления длительной микрофиляриемии Dirofilaria repens и первый опыт комбинированной терапии дирофиляриозд repens

Первый в России аутохтонный случай выявления длительной микрофиляриемии Dirofilaria repens и первый опыт комбинированной терапии дирофиляриозд repens

Abstract

A case of the longstandindg microfilaraemia due to Dirofilaria repens is presented as a 57-years-old female. This is the first report of the longstandindg microfilaraemia in a Russian patient due to infection of D. repens. The microfilariae of D. repens were detected due to multiple investigations of fresh drops of blood. The longstandindg microfilaraemia due to D. repens is discussed regarding their role in human pathology. As the larvae mature into adult wormes they migrate through blood vessels and the subdermal connective tissues causing pruritis, oedematous lesions on the skin, itching and pain as they pass beneath the conjunctivae and penetrate internal organs. The patient was successfully treated with doxycycline, albendazole and diethylcarbamazine.

Описан случай инвазии Dirofilaria repens у больной с неспецифической клинической симптоматикой, заразившейся в Московской области. В препаратах периферической крови больной были обнаружены личинки дирофилярий, которые выявлялись в течение двух месяцев. Данное наблюдение способствовало открытию пути миграции гельминта по кровеносным сосудам в организме человека и пути инвазирования внутренних органов, а также показало способность половозрелых дирофилярий спариваться и продуцировать личинки микрофилярии. Показана эффективность комбинированной терапии дирофиляриоза repens с использованием доксициклина, албендазола и диэтилкарбамазина. Отмечается объективная сложность диагностики дирофиляриоза repens и обсуждаются проблемы лечения.

Keywords

МИКРОФИЛЯРИЕМИЯ D. REPENS, ЭНДОСИМБИОНТ WOLBACHIА, ДОКСИЦИКЛИН, АЛБЕНДАЗОЛ, ДИЭТИЛКАРБАМАЗИН

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
gold