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Фенотипы бронхиальной астмы у детей и дифференцированная тактика диагностики и лечения

Фенотипы бронхиальной астмы у детей и дифференцированная тактика диагностики и лечения

Abstract

Бронхиальная астма самое распространённое хроническое заболевание дыхательной системы у детей. Своевременная диагностика затруднительна, особенно в раннем возрасте вследствие патофизиологической и клинической гетерогенности заболевания. Наиболее трудна для дифференцированного подхода тяжёлая бронхиальная астма. Выделение фенотипов и эндотипов с изучением соответствующих биологических маркеров ведёт к патогенетически обоснованной базисной терапии.

Bronchial asthma is the most widespread chronic respiratory desease in childhood. Timely diagnostic is difficult, especcially in early childhood due to pathophysiological and clinical geterogeneity. Severe Asthma in children is the most hard for identification and treatment. Defining asthma phenotypes and endotypes, study of corresponding biomarkers will lead to pathogenetic targeted treatment.

Keywords

БРОНХИАЛЬНАЯ АСТМА, КОНТРОЛИРУЕМОСТЬ, ФЕНОТИП, ЭНДОТИП, БАЗИСНАЯ ТЕРАПИЯ, ТРИГГЕРЫ, БИОМАРКЕРЫ, ИНГАЛЯЦИОННЫЕ ГЛЮКОКОРТИКОСТЕРОИДЫ, АНТИЛЕЙКОТРИЕНОВЫЕ ПРЕПАРАТЫ

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
bronze