Powered by OpenAIRE graph
Found an issue? Give us feedback

Коррекция гиперспленизма при хирургическом лечении портальной гипертензии

Коррекция гиперспленизма при хирургическом лечении портальной гипертензии

Abstract

_________________________________________________________________________________ Цель. Изучить эффективность дистальных спленоренальных анастомозов без перевязки селезеночной артерии и операции Sugiura-Futagawa в коррекции гиперспленизма. Материалы и методы. Прооперировано 66 пациентов по поводу цирроза печени различной этиологии, портальной гипертензии, осложненной варикозным расширением вен пищевода, гиперспленизмом. Мужчин 36, женщин 30. Возраст пациентов колебался от 16 до 69 лет и в среднем составил 40,13 ± 9,03 г. Сорока пяти больным, госпитализированным в экстренном порядке по поводу продолжающегося кровотечения из варикозно-расширенных вен пищевода или же сразу после него, при неэффективности консервативного и эндоскопического лечения была выполнена модифицированная нами разобщающая операция Sugiura-Futagawa. Результаты. Установлено, что выполнение операции Sugiura-Futagawa с удалением селезенки позволяет в раннем и отдаленном послеоперационных периодах корригировать все признаки гиперспленизма. После наложения дистальных спленоренальных анастомозов без перевязки селезеночной артерии сразу после операции достоверно повышалось количество лейкоцитов, а через год обнаружена лишь тенденция к повышению количества тромбоцитов и эритроцитов по сравнению с дооперационным уровнем. Выводы. Предикторами коррекции гиперспленизма в отдаленном периоде после декомпрессирующей воротную систему операции служат исходный уровень эритроцитов, лейкоцитов, активность трансаминаз, объемная скорость кровотока по воротной вене.

Aim. The aim of the study was to investigate the efficiency of the distal splenorenal anastomoses without splenic artery ligation as well as Sugiura-Futagawa surgery in correction of hypersplenism. Materials and methods. Sixty six patients were operated for hepatic cirrhosis (HC) of various etiology, portal hypertension (PH), complicated by esophageal varicose veins dilatation (EVVD), hypersplenism. There were 36 men and 30 women. The patients’ age ranged from 16 to 69 years with a mean age of 40,13 ± 9,03 years. Forty five patients, urgently hospitalized in connection with continued hemorrhage from the EVVD or immediately after it, in case of ineffective conservative and endoscopic treatment underwent Sugiura-Futagawa surgery, modified by us. Results. Sugiura-Futagawa surgery with splenectomy permits to correct all the symptoms of hypersplenism in the early and long-term postoperative periods. After applying distal splenorenal anastomoses without splenic artery ligation, the number of leucocytes significantly increased just after the surgery, and one year later there was only a tendency to rise in the amount of platelets and erythrocytes compared to the preoperative level. Conclusions. Predictors of hypersplenism correction in the long-term period following the portal system decompressing surgery are the initial erythrocyte and leukocyte levels, transaminase activity, portal volumetric blood circulation.

Keywords

ГИПЕРСПЛЕНИЗМ,ПОРТАЛЬНАЯ ГИПЕРТЕНЗИЯ,ДИСТАЛЬНЫЙ СПЛЕНОРЕНАЛЬНЫЙ АНАСТОМОЗ,ОПЕРАЦИЯ SUGIURA-FUTAGAWA,HYPERSPLENISM,PORTAL HYPERTENSION,DISTAL SPLENORENAL ANANSTOMOSIS,SUGIURA-FUTAGAWA SURGERY

  • BIP!
    Impact byBIP!
    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    0
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Average
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Average
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Average
Powered by OpenAIRE graph
Found an issue? Give us feedback
selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
gold