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Анналы клинической и экспериментальной неврологии
Article . 2014
Data sources: CyberLeninka - Russian open access scientific library
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Экспрессия Pgp в клетках нейроваскулярной единицы при перинатальном гипоксически-ишемическом повреждении головного мозга

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 2014 Russian Publisher:Федеральное государственное бюджетное научное учреждение «Научный центр неврологии»Journal:Анналы клинической и экспериментальной неврологии (issn: 2075-5473, eissn: 2409-2533 , Copyright policy )

Экспрессия Pgp в клетках нейроваскулярной единицы при перинатальном гипоксически-ишемическом повреждении головного мозга

Abstract

В статье приведены результаты исследований, выполненных на 35 крысятах возрастом 10 сут. Оценены особенности экспрессии Р-гликопротеина (Pgp) в клетках головного мозга нейрональной, астроцитарной и эндотелиальной природы после перенесенного перинатального гипоксически-ишемического повреждения. Обнаружено значимое увеличение экспрессии Pgp в астроцитах в первые 4 часа ишемии, в нейронах и эндотелиоцитах в первые 12 часов ишемии. Обсуждается роль увеличения экспрессии Pgp в патогенезе ишемического повреждения головного мозга.

Keywords

Р-ГЛИКОПРОТЕИН/PGP,ПЕРИНАТАЛЬНОЕ ПОВРЕЖДЕНИЕ ГОЛОВНОГО МОЗГА,НЕЙРОВАСКУЛЯРНАЯ ЕДИНИЦА

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
gold