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Изменение концентрации эссенциальных микроэлементов в плазме крови у детей с хроническими заболеваниями желудочно-кишечного тракта, имеющих различную массу тела

Изменение концентрации эссенциальных микроэлементов в плазме крови у детей с хроническими заболеваниями желудочно-кишечного тракта, имеющих различную массу тела

Abstract

The article deals with the characteristics of alterations ofmineral metabolism indi-cators in children of various age with chronic diseases of gastrointestinal tract and having body mass of normal and different surplus degrees. The sample consisted of 127 children aged from 6 to 15 years with chronic gastroduodenitis, pancreatitis and cholecystitis. The concentration of bioelements in plasma was determined us-ing the technique ofmass spectrometry with inductively coupled plasma. The study established the increase of concentration ofmolybdenum 4.3 times, chrome 8.4 times and selenium -1.36 times. The revealed bioelemental misbalance im-pacts the overall health of children and course of disease and hence has to be ac-counted in case of application of treatment targeted to the correction of mineral metabolism.

Цель исследования — изучить особенности изменений показателей минерального обмена при хронических заболеваниях желудочно-кишечного тракта у детей различного возраста с нормальной и избыточной в разной степени массой тела. Обследовано 127 детей в возрасте от 6 до 15 лет, у которых были выявлены хронические гастродуоденит, панкреатит, холецистит. Концентрацию биоэлементов в плазме крови определяли методом масс-спектрометрии с индуктивно связанной плазмой. В ходе исследования установлено повышение концентрации молибдена в 4,3 раза, хрома в 8,4 раза и селена в 1,36 раза. Выявленный биоэлементный дисбаланс оказывает влияние на общее состояние здоровья детей, течение заболевания и должен учитываться при проведении терапии, направленной на коррекцию минерального обмена.

Keywords

ХРОМ, МОЛИБДЕН, СЕЛЕН, МАСС-СПЕКТРОМЕТРИЯ С ИНДУКТИВНО СВЯЗАННОЙ ПЛАЗМОЙ, ХРОНИЧЕСКИЕ ЗАБОЛЕВАНИЯ ЖЕЛУДОЧНО-КИШЕЧНОГО ТРАКТА, ДЕТИ

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
gold