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Характеристика микрофлоры мочевыделительной системы у больных с позвоночно-спинномозговой травмой

Характеристика микрофлоры мочевыделительной системы у больных с позвоночно-спинномозговой травмой

Abstract

Characteristics of urinary tract microflora in patients with spinal cord injury Bludenov D.N., Naumenko Z.S., Godovyh N.V., Prudnikova O.G., Shchurova E.N. Federal State Budget Institution – The Russian Ilizarov Scientific Center Restorative Traumatology and Orthopaedics of the Ministry of Health and Social Development of Russia, Kurgan, Russia. (640014, Kurgan, street M. Ulyanova, 6) e-mail: dimon4581@inbox.ru A hospital-based study was conducted and urine samples were collected from 42 clinical cases of spinal cord injury and tested bacteriologically using standard procedures. Urinary tract infections were detected from 78.6% of the total patients. The predominant pathogens isolated belong to Enterobacteria group. Correlation between species of uropathogens isolated and micturion in patients as well as antibiotic resistance of bacteria were analysed. Enterobacteria (E. colli, K. pneumoniae), isolated from patients with urine bradyuria, incontinence or epicystosome were shown to have high resistance to antibiotics, caused by extended-spectrum-B-lactamase production (ESBL). Microbial profile did not depend on the kind of moving disorders, however, the frequency of isolation of pathogens was the lowest in patients with spastic paraparesis of lower limbs.

Характеристика микрофлоры мочевыделительной системы у больных с позвоночно-спинномозговой травмой Блюденов Д. Н., Науменко З. С., Годовых Н. В., Прудникова О. Г., Щурова Е. Н. ФГБУ «РНЦ «ВТО» им. акад. Г.А. Илизарова Минздравосоцразвития России», Курган, Россия. (640014, г. Курган, ул. М. Ульяновой, 6.) e-mail: dimon4581@inbox.ru Проведено бактериологическое исследование мочи с помощью стандатных тестов у 42 больных с позвоночно-спинномозговой травмой. Инфекционные осложнения мочевыводящих путей были определены у 78, 6 % от общего числа пациентов. Большинство бактерий относились к группе энтеробактерий. Была проведена оценка зависимости спектра возбудителей от особенностей мочевыделения пациентов, а также проанализированы антибиотикограммы возбудителей. Высокий уровень резистентности, обусловленный продукцией β–лактамаз расширенного спектра (БЛРС), выявлялся у энтеробактерий (E. coli, K. pneumoniae) у больных с задержкой, недержанием мочи и эпицистостомой. Спектр возбудителей не зависел от характера двигательных нарушений, хотя частота выделения микроорганизмов отличалась и была самой низкой у пациентов с нижним парапарезом.

Keywords

МИКРОБИОЛОГИЧЕСКАЯ ОЦЕНКА УРОПАТОГЕНОВ, ПОЗВОНОЧНО-СПИННОМОЗГОВАЯ ТРАВМА, АНТИБИОТИКОРЕЗИСТЕНТНОСТЬ, МОЧЕВЫВОДЯШИЕ ПУТИ.

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
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