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Новый источник десцеметотрансплантата для выполнения DMEK

Новый источник десцеметотрансплантата для выполнения DMEK

Abstract

В современной кератотрансплантологии отмечается ежегодный рост частоты выполнения кератопластик. Вместе с тем проблема недостатка трансплантационного материала весьма актуальна для всех стран, особенно для Российской Федерации. В связи с этим рациональное использование донорской ткани является неотъемлемой задачей кератотрансплантолога. В условиях ex vivo продемонстрирована возможность выкраивания десцеметовой мембраны с эндотелием для выполнения DMEK из сквозного кератоконического диска роговицы пациента, обретенного в ходе сквозной кератопластики. Предложенный источник трансплантационной ткани характеризуется относительной доступностью и высокой плотностью эндотелиальных клеток. Подобный подход не требует дополнительных исследований, времени и консервации трансплантируемой ткани.

The modern keratotrtansplantology is characterized by annual increase of keratoplastic application. Besides, the issue of lacking of transplantation material is of major actuality for all countries and especially the Russian Federation. As a result, the rational application of donor tissue becomes an integral task of keratotranplantologist. The possibility of cutting out Descemet’s membrane with endothelium from end-to-end cornea disc of patient acquired during end-to-end keratoplastics to implement DMEK is demonstrated in vivo. The proposed source of transplant tissue is characterized by relative availability and higher density of endothelium cells. This kind of approach has no requirements in additional research studies, time and conservation of transplant tissue.

Keywords

КЕРАТОКОНУС, ТРАНСПЛАНТАЦИЯ РОГОВИЦЫ, KERATO^NUS

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
bronze