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Особенности контаминации пародонтопатогенной микрофлорой полости рта у пациентов с болезнью Паркинсона

Особенности контаминации пародонтопатогенной микрофлорой полости рта у пациентов с болезнью Паркинсона

Abstract

Цель исследования изучить спектр доминирующих условно-патогенных микроорганизмов в биоценозе полости рта у пациентов с болезнью Паркинсона. Материал и методы. Проведен анализ качественного составапародонтопатогенногомикробиоценозаротовойполостиу38пациентовсболезньюПаркинсонаметодом ПЦР-диагностики. Результаты и их обсуждение. Установлено, что доминирующей микрофлорой пародонтального кармана были бактерии рода Tannerella forsythensis (высевались в 73,6% случаев), частота встречаемости Prevotella intermedia и Porphyromonas gingivalis составила 63,2%, Acinobacillus actinomycetemcomitan s 60,5%, реже всего (и только в ассоциациях из 3-5 бактерий) встречалась Treponema denticola в 55,3% случаях. Выявлена положительная корреляционная зависимость между показателями «глубина пародонтального кармана» и «частота высеваемости пародонтопатогенных штаммов микроорганизмов», r=0,785.

Aim to explore the range of dominant conditionally pathogenic microorganisms in oral cavity microflora in patients with Parkinson's disease. Materialandmethods. Weanalyzedthequalitativecompositionofparodontopatogenic microflora of the oral cavity in 38 patients with Parkinson's disease by PCR diagnostics. Results and discussion. Found that the dominant microflora of periodontal pockets were bacteria of the genus Tannerella forsythensis (sown in 73,6% of cases), the incidence of Prevotella intermedia and Porphyromonas gingivalis was 63,2%, actinomycetemcomitans 60,5%, revealed less often (and only in the associations with 3-5 bacteria), Treponema denticola in 55,3% of cases. A positive correlation in «periodontal pocket depth» and «frequency of the isolation of microbial strains parodontopatogennyh» (r=0,785) demonstrated.

Keywords

БОЛЕЗНЬ ПАРКИНСОНА, ПАРОДОНТОПАТОГЕННАЯ МИКРОФЛОРА, СОСТОЯНИЕ ТКАНЕЙ ПАРОДОНТА, ПЦР-ДИАГНОСТИКА, PARKINSON''S DISEASE

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
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