
The purpose. This study was aimed at examining the influence of thrombophilic conditions on pulmonary embolism (PE) and the efficacy of thrombolytic therapy. Materials and methods. The effects of haemostatic disorders on the frequency of recurrent PE, phlebothrombosis and inferior vena cava thrombosis were studied in 70 patients with acute massive PE. Results. Hematogenic thrombophilia was detected in 25,7 % of patients. It was found that thrombosis and embolism in the vena cava filter were observed more frequently in patients with hematogenic thrombophilia than in patients with pulmonary embolism of unknown etiology. Conclusions. It was proved that differentiated treatment of hematogenic thrombophilias can significantly reduce the risk of recurrent thrombotic episodes in patients with acute pulmonary embolism.
Цель. Оценка влияния тромбофилических состояний на течение ТЭЛА и эффективность тромболитической терапии. Материалы и методы. Изучено влияние нарушений гемостаза на частоту рецидивов ТЭЛА, флеботромбоза и тромбоза нижней полой вены (НПВ) у 70 больных с острой массивной ТЭЛА. Результаты. Гематогенная тромбофилия (ГТ) была обнаружена у 25,7 % пациентов. Выяснилось, что у больных с гематогенными тромбофилиями тромбозы и эмболии в кава-фильтр наблюдались чаще, чем у пациентов с ТЭЛА неустановленной этиологии. Выводы. Доказано, что проведение дифференцированной терапии ГТ у больных с острой ТЭЛА позволяет существенно снизить риск повторных тромботических эпизодов.
ТРОМБОЗ, ОСТРАЯ ТРОМБОЭМБОЛИЯ ЛЁГОЧНЫХ АРТЕРИЙ, ГЕМАТОГЕННЫЕ ТРОМБОФИЛИИ
ТРОМБОЗ, ОСТРАЯ ТРОМБОЭМБОЛИЯ ЛЁГОЧНЫХ АРТЕРИЙ, ГЕМАТОГЕННЫЕ ТРОМБОФИЛИИ
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