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Влияние тромбофилических состояний на течение ТЭЛА и эффективность Тромболитический терапии

Влияние тромбофилических состояний на течение ТЭЛА и эффективность Тромболитический терапии

Abstract

The purpose. This study was aimed at examining the influence of thrombophilic conditions on pulmonary embolism (PE) and the efficacy of thrombolytic therapy. Materials and methods. The effects of haemostatic disorders on the frequency of recurrent PE, phlebothrombosis and inferior vena cava thrombosis were studied in 70 patients with acute massive PE. Results. Hematogenic thrombophilia was detected in 25,7 % of patients. It was found that thrombosis and embolism in the vena cava filter were observed more frequently in patients with hematogenic thrombophilia than in patients with pulmonary embolism of unknown etiology. Conclusions. It was proved that differentiated treatment of hematogenic thrombophilias can significantly reduce the risk of recurrent thrombotic episodes in patients with acute pulmonary embolism.

Цель. Оценка влияния тромбофилических состояний на течение ТЭЛА и эффективность тромболитической терапии. Материалы и методы. Изучено влияние нарушений гемостаза на частоту рецидивов ТЭЛА, флеботромбоза и тромбоза нижней полой вены (НПВ) у 70 больных с острой массивной ТЭЛА. Результаты. Гематогенная тромбофилия (ГТ) была обнаружена у 25,7 % пациентов. Выяснилось, что у больных с гематогенными тромбофилиями тромбозы и эмболии в кава-фильтр наблюдались чаще, чем у пациентов с ТЭЛА неустановленной этиологии. Выводы. Доказано, что проведение дифференцированной терапии ГТ у больных с острой ТЭЛА позволяет существенно снизить риск повторных тромботических эпизодов.

Keywords

ТРОМБОЗ, ОСТРАЯ ТРОМБОЭМБОЛИЯ ЛЁГОЧНЫХ АРТЕРИЙ, ГЕМАТОГЕННЫЕ ТРОМБОФИЛИИ

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
gold