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Исследование аэрогенной нагрузки на состояние буккальных эпителиоцитов у больных сахарным диабетом

Исследование аэрогенной нагрузки на состояние буккальных эпителиоцитов у больных сахарным диабетом

Abstract

Изучались распространенность сахарного диабета (СД) 2-го типа и влияние на нее загрязнителей атмосферного воздуха среди жителей районов г. Воронежа с разным уровнем аэрогенной нагрузки с дальнейшим исследованием у них электрокинетической активности (ЭКА) клеток буккального эпителия. Заболеваемость населения СД 2-го типа рассмотрена по данным формы № 12, влияние на нее аэрогенной нагрузки с помощью корреляционного анализа. У 22 больных СД 2-го типа средней степени тяжести и 23 практически здоровых лиц исследована ЭКА. Коэффициент корреляции между показателями заболеваемости СД 2-го типа и техногенного загрязнения воздушной среды оксидом меди составил 0,4 в условно чистом и 0,8 в промышленном районах. У больных СД 2-го типа ЭКА значимо ниже по сравнению с практически здоровыми людьми. Выявлена взаимосвязь заболеваемости СД 2-го типа у лиц, проживающих на контрастных территориях, и загрязнением воздуха оксидом меди. Изменения ЭКА буккальных эпителиоцитов при СД 2-го типа являются косвенным отражением функционального состояния организма.

The aim was to study diabetes 2 prevalence and atmospheric pollution effects among patients under different anthropogenic loads, and to study buccal epithelium electrokinetic activity. Methods. Diabetes 2 morbidity was analyzed according to Form N 12. Aerogenic load effect has been studied with use of the correlation analysis method. Epithelium electrokinetic activity (%) has been examined in 22 patients with diabetes 2 and 23 healthy persons. Results. Coefficient correlation between diabetes 2 morbidity and technogenic atmospheric pollution by copper oxide was 0.4 in relatively clean and 0.8 in industrial districts. Epithelium electrokinetic activity (%) in patients with diabetes 2 was lower than in healthy persons (17.5 ± 2.0 and 36.7 ± 2.5, respectively). Conclusion. Interrelation between diabetes 2 morbidity among patients from contrast areas and copper oxide pollution has been stated. Change of electrokinetic activity of buccal epithelial cells at diabetes 2 indirectly reflects an organism functional state.

Keywords

БУККАЛЬНЫЙ ЭПИТЕЛИЙ, ЭЛЕКТРОКИНЕТИЧЕСКАЯ АКТИВНОСТЬ, САХАРНЫЙ ДИАБЕТ 2-ГО ТИПА, ЗАГРЯЗНЕНИЕ АТМОСФЕРНОГО ВОЗДУХА

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
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