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Профилактическое назначение антибактериальных препаратов беременным женщинам, колонизированным стрептококками группы в

Профилактическое назначение антибактериальных препаратов беременным женщинам, колонизированным стрептококками группы в

Abstract

Стрептококки группы В (СГВ), Streptococcus agalactiae, являются возбудителями тяжелой инфекции плода и новорожденного ребенка. Целью исследования явилась оценка эффективности применения антибактериальных препаратов у женщин в III триместре беременности для профилактики стрептококковой В инфекции. Изучено течение родов и послеродового периода у 70 женщин, колонизированных стрептококками группы В, получавших и не получавших антибактериальные перпараты в III триместре беременности. Оценено также состояние новорожденных детей этих женщин. У беременных, получавших антибактериальные препараты в III триместре беременности, достоверно реже имели место несвоевременное излитие околоплодных вод, преждевременные роды, субинволюция матки. Реже была отмечена асфиксия новорожденных. СГВ достоверно чаще (в 43,5 % случаев) были выделены у детей, родившихся у матерей, не получавших антибактериальные препараты во время беременности. У 26,1 % этих детей диагностирована внутриутробная инфекция. Таким образом, применение антибактериальных препаратов в III триместре беременности при выявлении СГВ в моче в любом количестве, одновременном выявлении этих микроорганизмов в моче и отделяемом влагалища в концентрации более 104 КОЕ/мл снижает частоту преждевременных родов, послеродовых осложнений, а также асфиксии новорожденных и внутриутробной инфекции стрептококковой В этиологии.

Group B streptococcus (GBS), Streptococcus agalactiae, are the causative agents of severe infection of the fetus and newborn child. The aim of the study was to evaluate the efficacy of antibacterial drugs in women in the III trimester of pregnancy for the prevention of B streptococcal infection. Studied during childbirth and the postpartum period, 70 women colonized by group B streptococcus, treated and not treated with antibacterial perparaty in the III trimester of pregnancy. Evaluated as a new-born children of these women. In pregnant women who received antibiotics in the III trimester of pregnancy, significantly fewer were delayed rupture of membranes, preterm labor, subinvolution uterus. Less common was marked asphyxia. Group B streptococcus significantly more frequently (in 43.5 % of cases) were identified in children born to mothers who did not receive antibiotics during pregnancy. In 26.1 % of these children diagnosed with intrauterine infection. Thus, the use of antimicrobials in the III trimester of pregnancy in detecting GBS in the urine in any quantity, simultaneous detection of these microorganisms in urine and vaginal discharge of a concentration of greater than 104 CFU/ml reduces the rate of preterm birth, postpartum complications, and neonatal asphyxia and intrauterine infection B streptococcal etiology.

Keywords

СТРЕПТОКОККИ ГРУППЫ В,GROUP B STREPTOCOCCUS,КОЛОНИЗАЦИЯ НОВОРОЖДЕННЫХ,COLONIZATION OF NEWBORNS,ВНУТРИУТРОБНАЯ ИНФЕКЦИЯ,INTRAUTERINE INFECTION,АНТИБАКТЕРИАЛЬНАЯ ТЕРАПИЯ,ANTIBIOTIC THERAPY

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
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