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Диагностические аспекты остеопенического синдрома у больных сахарным диабетом типа 1

Диагностические аспекты остеопенического синдрома у больных сахарным диабетом типа 1

Abstract

The condition of a bone fabric at 102 sick diabetes mellitus type 1 (48 men and 54 women, middle age (38,2 ± 12,2) years) is studied, also are specified influence of various factors on development osteopenic syndrome. Research methods included clinical and history of development of disease, beam, biochemical, statistical methods of processing of results. As a result of research it has been revealed that indicators of bone durability at sick of a diabetes corresponded osteopenia which was accompanied by infringement micro-arhcitecture bones in the form of decrease in relative volume trabecular bones and quantities trabecula. Osteosonographie it was accompanied by changes of markers of a bone metabolism (osteocalcin and C-trailer tilopeptid) testifying to activation of processes osteolysis at sick of a diabetes.

Изучено состояние костной ткани у 102 больных сахарным диабетом типа 1 (СД-1) (48 мужчин и 54 женщины, средний возраст (38,2 ± 12,2) года) и уточнено влияние различных факторов на развитие остеопенического синдрома. Методы исследования включали клинико-анамнестические, лучевые, биохимические, статистические методы обработки результатов. Выявлено, что показатели костной прочности у больных СД-1 соответствовали остеопении, которая сопровождалась нарушением микроархитектоники кости в виде снижения относительного объема трабекулярной кости и количества трабекул. Ультразвуковая остеометрия сопровождалась изменениями маркеров костного метаболизма (остеокальцина и С-концевого телопептида), свидетельствуя об активации процессов резорбции у пациентов с СД-1.

Keywords

ОСТЕОПОРОЗ, САХАРНЫЙ ДИАБЕТ, УЛЬТРАЗВУКОВАЯ ОСТЕОМЕТРИЯ

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
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