
The condition of a bone fabric at 102 sick diabetes mellitus type 1 (48 men and 54 women, middle age (38,2 ± 12,2) years) is studied, also are specified influence of various factors on development osteopenic syndrome. Research methods included clinical and history of development of disease, beam, biochemical, statistical methods of processing of results. As a result of research it has been revealed that indicators of bone durability at sick of a diabetes corresponded osteopenia which was accompanied by infringement micro-arhcitecture bones in the form of decrease in relative volume trabecular bones and quantities trabecula. Osteosonographie it was accompanied by changes of markers of a bone metabolism (osteocalcin and C-trailer tilopeptid) testifying to activation of processes osteolysis at sick of a diabetes.
Изучено состояние костной ткани у 102 больных сахарным диабетом типа 1 (СД-1) (48 мужчин и 54 женщины, средний возраст (38,2 ± 12,2) года) и уточнено влияние различных факторов на развитие остеопенического синдрома. Методы исследования включали клинико-анамнестические, лучевые, биохимические, статистические методы обработки результатов. Выявлено, что показатели костной прочности у больных СД-1 соответствовали остеопении, которая сопровождалась нарушением микроархитектоники кости в виде снижения относительного объема трабекулярной кости и количества трабекул. Ультразвуковая остеометрия сопровождалась изменениями маркеров костного метаболизма (остеокальцина и С-концевого телопептида), свидетельствуя об активации процессов резорбции у пациентов с СД-1.
ОСТЕОПОРОЗ, САХАРНЫЙ ДИАБЕТ, УЛЬТРАЗВУКОВАЯ ОСТЕОМЕТРИЯ
ОСТЕОПОРОЗ, САХАРНЫЙ ДИАБЕТ, УЛЬТРАЗВУКОВАЯ ОСТЕОМЕТРИЯ
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