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Современные представления о микроспоридиозе человека

Современные представления о микроспоридиозе человека

Abstract

Микроспоридиоз повсеместно распространенное оппортунистическое заболевание, обычно проявляющееся у пациентов с ослабленным иммунитетом: у больных СПИДом или реципиентов трансплантатов органов. Инфекционным агентом являются родственные грибам облигатные внутриклеточные паразиты микроспоридии. Вместе с криптоспоридиями и представителями рода Cytomegalovirus данные паразиты представляют собой самыхраспространенных возбудителей диареи у ВИЧ-инфицированных больных. Чаще всего наблюдается кишечная форма микроспоридиоза, однако данные патогены могут поражать практически все органы человеческого организма: глаза, легкие, мышцы, органы нервной системы. В обзоре представлены актуальные данные об этиологии, патогенезе, эпидемиологии, клинических признаках, диагностике, современных методах и перспективах лечения микроспоридиоза.

Microsporidiosis is an ubiquitous opportunistic disease that usually appears in immunocompromised patients: AIDS patients or organ-transplant recipients. The infectious agents of disease are fungi-related obligate intracellular parasites microsporidia. Alongside with Cryptosporidium and Cytomegalovirus, these parasites are the most common causative agents of diarrhea in HIV-infected patients. Intestinal form of microsporidiosis has been most frequently observed, but microsporidia can affect almost any organs of the human body, eyes, lungs, muscles, organs of the nervous system. The present paper overviews the current data on the etiology, pathogenesis, epidemiology, clinical presentation, diagnosis and treatment methods of microsporidiosis.

Keywords

МИКРОСПОРИДИИ, МИКРОСПОРИДИОЗ, ОППОРТУНИСТИЧЕСКИЕ ИНФЕКЦИИ, ПАРАЗИТАРНЫЕ ЗАБОЛЕВАНИЯ, ИММУНОДЕФИЦИТ

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
bronze
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