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Влияние бактериального липополисахарида на эластичность легочной ткани: модельные испытания

Влияние бактериального липополисахарида на эластичность легочной ткани: модельные испытания

Abstract

In our research we try to determine the mechanical properties of lung tissue in an experimental model of acute lung injury initialize by mikroaerozol inhalation of single lipopolysacharide E. coli О128 : B12 in 17 rats. Mikroaerozol need for better penetration of the respiratory apparatus of the lungs. The dynamics of elongation in normal lung tissue and after inhalation of saline solution as a carrier apyrogenic and with a variance of LPS is studied. It is found that inhalation of LPS is accompanied by a decrease in the elasticity of the lung tissue.

С целью определения механических свойств легочной ткани в экспериментальной модели острого легочного повреждения в опытах на 17 белых крысах проводили однократные ингаляции липополисахарида E. coli О128 : B12 в виде микроаэрозоля для лучшего проникновения в респираторный аппарат легких. Проанализировали динамику растяжимости легочной ткани в норме и после ингаляции водно-солевого носителя как апирогенного, так и с дисперсией ЛПС. Было установлено, что ингаляция ЛПС сопровождается снижением эластичности легочной ткани.

Keywords

ЛИПОПОЛИСАХАРИД, ИНГАЛЯЦИОННОЕ ПОСТУПЛЕНИЕ, ЛЕГКИЕ, МЕХАНОТРАНСДУКЦИЯ

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
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