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Плазмоцитарный пододерматит кошек

Плазмоцитарный пододерматит кошек

Abstract

Плазмоцитарный пододерматит кошек является достаточно редкой болезнью подушечек лап. Клиническим проявлением плазмоцитарного пододерматита является безболезненное опухание и размягчение подушечек, которые могут изъязвляться, что может приводить к кровотечению и хромоте. При этом развивается вторичная бактериальная инфекция. Лабораторные тесты, подтверждающие диагноз, включают цитологическое и гистологическое исследования. Этиопатогенез до конца не изучен, персистирующая гипергаммаглобулинемия в сыворотке крови, наличие плазмоцитарного инфильтрата и положительный ответ на иммуносупрессивную терапию позволяют подозревать иммуноопосредованную причину болезни. Имеются данные о сопутствующем течении плазмоцитарного пододерматита с плазмоцитарным стоматитом, амилоидозом почек и иммуноопосредованным гломерулонефритом. Плазмоцитарный пододерматит отвечает на иммуносупрессивную терапию, в некоторых случаях проводится хирургическое удаление пораженных тканей. Возможна также спонтанная ремиссия.

Feline plasma cell pododermatitis is a rare skin disease of cat footpads. Clinically, feline plasma cell pododermatitis begins as a soft, nonpainful spongy swelling of footpads, which in some cases become ulcerated causing haemorrhage and lameness. Recurrent haemorrhages from ulcerated or nodular areas of a pad can occur as well as secondary bacte-rial infection. Laboratory tests include skin cytology or skin biopsy.The aetiopathogenesis is unknown, but persistent hy-pergammaglobulinemia, marked plasma cell tissue infiltrate and the beneficial response to immunomodulative therapy strongly suggest an immune-mediated basis for the disease. In some cats concurrent plasmacytic stomatitis, renal amyloidosis or immune-mediated glomerulonephritis is reported. Feline plasma cell pododermatitis responds well to immunosuppressive therapy and to wide surgical excision of affected footpads. In some cases, spontaneous remission of the lesions occurs.

Keywords

ПЛАЗМАТИЧЕСКИЕ КЛЕТКИ, ПОДОДЕРМАТИТ, КОШКА

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
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