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Оценка сердечной деятельности у детей, страдающих эпилепсией

Оценка сердечной деятельности у детей, страдающих эпилепсией

Abstract

У 48 детей младшего школьного возраста с различными формами эпилепсии, помимо клинико-анамнестического и общепринятого инструментального обследования, определялись уровень активности МВ-креатинфосфокиназы (МВ-КФК) сыворотки крови и показатели вариабельности ритма сердца (ВРС). Согласно полученным результатам пациенты с эпилепсией разделились на подгруппы: с выраженными, умеренными и без нарушений сердечной деятельности. Установлено повышение МВ – креатинфосфокиназы и снижение основных показателей вариабельности ритма сердца (ТР, LF) преимущественно в подгруппе с выраженными нарушениями сердечной деятельности. Изменения этих показателей оказались более чувствительными, чем общепринятые, и характеризуют степень выраженности миокардиальных нарушений. Сочетанное определение уровня активности МВ-креатинфосфокиназы и основных параметров вариабельности ритма сердца может служить дополнительным критерием оценки сердечной деятельности детей, страдающих эпилепсией.

In 48 primary school children with various forms of epilepsy in addition to clinical and anamnestic and conventional instrumental examination determined the level of activity of creatine kinase MB (CK-MB) serum and heart rate variability (HRV). According to the results, patients with epilepsy were divided into subgroups with severe, moderate and no abnormality of the heart. Found an increase in MV creatine kinase and reduction of the main indicators of heart rate variability (TP, LF) mainly in the subgroup with severe cardiac activity. Changing these parameters proved to be more sensitive than conventional and characterize the severity of myocardial disorders. Combined to determine the level of activity and creatine phosphokinase-MB main parameters of heart rate variability may serve as additional criteria for evaluation of cardiac function of children with epilepsy.

Keywords

НАРУШЕНИЕ СЕРДЕЧНОЙ ДЕЯТЕЛЬНОСТИ, ВАРИАБЕЛЬНОСТЬ РИТМА СЕРДЦА, МВ-КРЕАТИНФОСФОКИНАЗА, ЭПИЛЕПСИЯ, ДЕТИ МЛАДШЕГО ШКОЛЬНОГО ВОЗРАСТА

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
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