
В ходе исследования ВИЧ-инфицированныи: лиц с использованием новой пятицветной панели CytoDiff™ для проточной цитофлюориметрии обнаружен дисбаланс в субпопуляциях лейкоцитов. Это проявлялось значительным снижением общего количества лимфоцитов, а также CD16 +-лимфоцитов, В-лимфоцитов и эозинофилов с одновременным повышением уровня CD16 +-моноцитов, нейтрофилов и незрелый: В-лимфоцитов. После проведения высокоактивной антиретровирусной терапии (ВААРТ) у пациентов наблюдалось снижение вирусной нагрузки при одновременном повышении общего уровня лимфоцитов, CD16 +-лимфоцитов, В-лимфоцитов, а также уменьшение количества CD16 +-моноцитов, нейтрофилов и незрелый: В-лимфоцитов.
The study of HIV-infected patients using new five-color panel CytoDiff for flow cytofluorometry revealed the imbalance in subpopulations of leukocytes. The manifestations consisted in significant decrease of total amount of lymphocytes and also CD16+ lymphocytes, B-lymphocytes and eosinocytes with synchronous increase of level of CD16+ monocytes, neutrophils and immature B-lymphocytes. After application to patients of highly active anti-retroviral therapy occurred decrease of viral load under synchronous increase of total level of lymphocytes, CD16+ lymphocytes, B-lymphocytes and also decrease of amount of CD16+ monocytes, neutrophils and immature B-lymphocytes.
ВИЧ, ПАНЕЛЬ, CD16+-МОНОЦИТЫ, CD4+-ЛИМФОЦИТЫ, CD16+ MONOCYTES, CD4+ LYMPHOCYTES
ВИЧ, ПАНЕЛЬ, CD16+-МОНОЦИТЫ, CD4+-ЛИМФОЦИТЫ, CD16+ MONOCYTES, CD4+ LYMPHOCYTES
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