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Эндометриальная дисфункция: алгоритм гистологического и иммуногистохимического исследования

Эндометриальная дисфункция: алгоритм гистологического и иммуногистохимического исследования

Abstract

It is advisable to conduct a comprehensive study of the morphological assessment of the expression of endometrial estrogen and progesterone receptors, inflammatory markers in the second phase of the menstrual cycle in patients with impaired reproductive function (infertility, miscarriage, failed IVF attempts). The optimal period for investigation of endometrial dysfunction via endometrial biopsy is the second phase of the cycle (the period of “implantation window”). Creating a diagnostic algorithm, histological and immunohistochemical studies in the endometrial dysfunction will allow to justify the optimal choice of therapy.

У пациенток с нарушением репродуктивной функции (бесплодием, невынашиванием беременности, неудачными попытками ЭКО) целесообразно проведение комплексного морфологического исследования эндометрия c оценкой экспрессии рецепторов эстрогена, прогестерона, маркеров воспаления во второй фазе цикла. Оптимальным сроком для биопсии эндометрия при эндометриальной дисфункции является вторая фаза цикла (период «окна имплантации»). Создание алгоритма диагностики гистологического и иммуногистохимического исследования при эндометриальной дисфункции позволит обосновать оптимальный выбор терапии.

Keywords

ГИСТОЛОГИЧЕСКОЕ И ИММУНОГИСТОХИМИЧЕСКОЕ ИССЛЕДОВАНИЕ,ЭСТРОГЕН И ПРОГЕСТЕРОН,ЭНДОМЕТРИАЛЬНАЯ ДИСФУНКЦИЯ,БЕСПЛОДИЕ,ХРОНИЧЕСКИЙ ЭНДОМЕТРИТ,HISTOLOGICAL AND IMMUNOHISTOCHEMICAL STUDY,ESTROGEN AND PROGESTERONE,ENDOMETRIAL DYSFUNCTION,STERILIS,CHRONIC ENDOMETRITIS

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    popularity
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    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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Powered by OpenAIRE graph
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
bronze