Powered by OpenAIRE graph
Found an issue? Give us feedback
image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Reviews on Clinical ...arrow_drop_down
image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
addClaim

This Research product is the result of merged Research products in OpenAIRE.

You have already added 0 works in your ORCID record related to the merged Research product.

Влияние иммуномодуляторов в разных комбинациях на люцигенин-зависимую хемилюминесценцию в альвеолярных и перитонеальных макрофагах крови

Влияние иммуномодуляторов в разных комбинациях на люцигенин-зависимую хемилюминесценцию в альвеолярных и перитонеальных макрофагах крови

Abstract

In vitro the blood alveolar and peritoneal macrophages can be assessed as systems with limit possibilities for evaluation of antioxidant properties of immune modulators because we can assess only antiradical (anti-superoxide О2•) effect of them in these systems. Immune modulators in fifferent concentrations (0.1-20 mM) can induce prooxidant or antioxidant effect in these systems. The blood alveolar and peritoneal macrophages differentially react on adding of immune modulators with proved systemic antioxidant properties (metaprot, trekresan, polyoxydonium). Combination of immune modulators increases the possibility of appearance of intiradical properties in these cellular systems.

In vitro альвеолярные и перитонеальные макрофаги являются системами с ограниченной возможностью оценки антиоксидантных свойств иммуномодуляторов, поскольку в них можно оценить только антирадикальный (антисупероксидный О2•) эффект. В данных системах иммуномодуляторы в разных концентрациях (0,1-20 мМ) могут оказывать прооксидантное и антиоксидантное действия. Перитонеальные и альвеолярные макрофаги по-разному реагируют на добавление иммуномодуляторов с заведомо доказанными системными антиоксидантными свойствами (метапрот, трекрезан, полиоксидоний). Комбинирование иммуномодуляторов повышает вероятность выявления их антирадикальных свойств в данных клеточных системах.

Keywords

АЛЬВЕОЛЯРНЫЕ И ПЕРИТОНЕАЛЬНЫЕ МАКРОФАГИ,АНТИОКСИДАНТНЫЕ СВОЙСТВА,ИММУНОМОДУЛЯТОРЫ,МЕТАПРОТ,ТРЕКРЕЗАН,ПОЛИОКСИДОНИЙ,ALVEOLAR AND PERITONEAL MACROPHAGES,ANTIOXIDANT PROPERTIES,IMMUNE MODULATORS,METAPROT,TREKRESAN,POLYOXYDONIUM

  • BIP!
    Impact byBIP!
    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    0
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Average
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Average
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Average
Powered by OpenAIRE graph
Found an issue? Give us feedback
selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
bronze