Powered by OpenAIRE graph
Found an issue? Give us feedback
image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ http://cyberleninka....arrow_drop_down
image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
addClaim

This Research product is the result of merged Research products in OpenAIRE.

You have already added 0 works in your ORCID record related to the merged Research product.

Локализованные моды дисторсии в структуре двойной спирали днк

Локализованные моды дисторсии в структуре двойной спирали днк

Abstract

Up to the present, real mechanisms of some biological process including deoxyribonucleic acid (DNA) are unknown. Because of this, the biologists concentrate detailed attention to structural aspects to elucidate real mechanisms of replication processes repetition), transcription (the first stage of genetic cellular information realization which results in biosynthesis of ribonucleic acid (RNA) molecules on the matrix of DNA), and denaturation (process of protein molecules decomposition). In the present study, the attempt is made to suggest the equation of motion as the special form Ginsburg-Landau equation for the order parameters, and to investigate the dynamic properties of the system under consideration. The equation is based on the solution statistical problem of the defects ensemble behavior and describes the localized distortions in the DNA structure. It is shown that the dynamics of localized distortion modes is connected with the new type of critical phenomena structural-scaling transitions, which are typical for the nonequilibrium systems with slow dynamics. The form of the new order parameter the structural scaling parameter is established, which plays the role of effective temperature for the nonequilibrium system. The analysis of the automodel equations reveals the existence of three types of collective modes in the defects ensembles in the corresponding intervals of structural scaling parameter. The correspondence between the typical collective modes and three types universal statistical distributions is shown in the superstatistics of nonequilibrium systems with slow dynamics. The presumable connection between collective modes dynamics and transcription and replication mechanisms is discussed.

Так как реальные механизмы некоторых биологических процессов, включающие дезоксирибонуклеиновую кислоту (ДНК), до сих пор неизвестны, биологи уделяют все большее внимание структурным аспектам с целью выяснить действительные механизмы репликации (повторение процесса), транскрипции (первого этапа реализации генетической информации в клетке, результатом которого является биосинтез молекул рибонуклеиновой кислоты (РНК) на матрице ДНК) и денатурации (процесса расщепления белковых молекул). В настоящей работе сделаны попытки на основе решения статистической задачи о поведении ансамбля дефектов предложить уравнение движения в виде специальной формы уравнения Гинзбурга-Ландау для параметров порядка, отражающего поведение локализованных дисторсий в структуре ДНК, и исследовать динамические свойства данной системы. Показано, что динамика локализованных мод дисторсии может быть связана с новым типом критических явлений структурно-скейлинговыми переходами, которые характерны для неравновесных систем с «медленной динамикой». Установлен вид дополнительного параметра порядка для данных систем структурный параметр скейлинга, который играет роль «эффективных температур» неравновесной системы. Проведенный анализ автомодельных решений выявил существование трех типов коллективных мод в ансамблях дефектов в соответствующих интервалах структурного параметра скейлинга. Показано соответствие характерных коллективных мод трем типам универсальных статистических распределений в суперстатистике неравновновесных систем с медленной динамикой. Обсуждается возможная связь динамики коллективных мод с механизмами транскрипции и репликации.

Keywords

ДЕЗОКСИРИБОНУКЛЕИНОВАЯ КИСЛОТА (ДНК), ДВОЙНАЯ СПИРАЛЬ, СТРУКТУРА, АНСАМБЛЬ ДЕФЕКТОВ, СТАТИСТИЧЕСКИЙ АНАЛИЗ, ПАРАМЕТР ПОРЯДКА, СКЕЙЛИНГ, НЕРАВНОВЕСНЫЕ СИСТЕМЫ, DEOXYRIBONUCLEIC ACID (DNA)

  • BIP!
    Impact byBIP!
    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    0
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Average
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Average
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Average
Powered by OpenAIRE graph
Found an issue? Give us feedback
selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average