Powered by OpenAIRE graph
Found an issue? Give us feedback
image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Medical news of the ...arrow_drop_down
image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
addClaim

This Research product is the result of merged Research products in OpenAIRE.

You have already added 0 works in your ORCID record related to the merged Research product.

Цитокиновая регуляция и особенности аутоиммунитета при синдроме гипермобильности суставов

Цитокиновая регуляция и особенности аутоиммунитета при синдроме гипермобильности суставов

Abstract

The article presents the results of the study of bone cytokines indicators, hormones of bone metabolism and the levels of thyroid autoantibodies and autoantibodies to type-specific collagens in 146 patients with joint hypermobility syndrome (JHS). The prevalence of vitamin D deficiency was significantly higher in patients with JHS compared to the control. The deviations of the bone mediators ratio in patients with JHS were identified. The study has demonstrated the increased incidence of autoimmune thyroiditis in patients with JHS and significantly more frequent existence of antithyroid antibodies and the antibodies to I-II types collagen

У 146 пациентов с синдромом гипермобильности суставов (СГМС) изучены показатели остеоактивных цитокинов, гормонов костного метаболизма, уровни аутоантител к тиреоидным антигенам и типоспецифическим коллагенам. Отмечена высокая распространенность дефицита витамина D у больных с СГМС по сравнению с контролем, а также нарушение соотношений медиаторов, регулирующих остеогенез и отражающих собственную эндокринную функцию кости. Исследование продемонстрировало повышенную частоту аутоиммунного тиреоидита при СГМС и достоверно более частое носительство антитиреоидных антител и аутоантител к коллагенам I и II типов.

Keywords

СИНДРОМ ГИПЕРМОБИЛЬНОСТИ СУСТАВОВ,JOINT HYPERMOBILITY SYNDROME,КОСТНОЕ РЕМОДЕЛИРОВАНИЕ,BONE REMODELING,ЦИТОКИНЫ,CYTOKINES,АУТОИММУНИТЕТ,AUTOIMMUNITY,КОЛЛАГЕН,COLLAGEN

  • BIP!
    Impact byBIP!
    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    0
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Average
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Average
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Average
Powered by OpenAIRE graph
Found an issue? Give us feedback
selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
gold
Related to Research communities