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Влияние деполяризации мембраны нейронов супрахиазматического ядра на спайковую активность in vitro

Влияние деполяризации мембраны нейронов супрахиазматического ядра на спайковую активность in vitro

Abstract

На переживающих срезах гипоталамуса крыс исследованы особенности спайковой активности нейронов супрахиазматического ядра в условиях деполяризации их мембраны in vitro. Деполяризация мембраны приводила к росту активности клеток и снижению энтропии логарифма распределения межспайковых интервалов, являющейся мерой нерегулярности генерации спайков. Обсуждаются возможные механизмы, лежащие в основе данных эффектов.

The properties of spike activity of neurons of the suprachiasmatic nucleus during their membrane depolarisation in vitro are investigated on rat hypothalamic slices. Depolarisation of membrane caused an increase in activity of cells and a decrease in entropy log interspike interval distribution were used as a measure of spikes irregularity generation. Possible mechanisms of the effects are discussed.

Keywords

СУПРАХИАЗМАТИЧЕСКОЕ ЯДРО, ЦИРКАДИАННЫЕ РИТМЫ, НЕЙРОНЫ, СПАЙКОВАЯ АКТИВНОСТЬ, ДЕПОЛЯРИЗАЦИЯ МЕМБРАНЫ

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
bronze