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Клинико-морфологические показатели и фенотип циркулирующих лимфоцитов у больных мезангиопролиферативным гломерулонефритом

Клинико-морфологические показатели и фенотип циркулирующих лимфоцитов у больных мезангиопролиферативным гломерулонефритом

Abstract

Analyzed were the quantitative and functional characteristics of circulating lymphocytes subpopulations and their relationship with other indicators of severity of mesangioproliferative glomerulonephritis in 43 patients. Established was the dependence between the severity of the process and the activation of lymphoid populations of peripheral blood lymphocytes, as well as a marked correlation between the severity of renal damage and increased levels of circulating activated subpopulations of T-lymphocytes, which exhibit cytotoxic activity.

Проанализированы количественные и функциональные особенности субпопуляций циркулирующих лимфоцитов и их связи с другими показателями тяжести мезангиопролиферативного гломерулонефрита у 43 пациентов. Выявлены зависимость между тяжестью процесса и активацией лимфоидных популяций лимфоцитов периферической крови, а также выраженная корреляция между тяжестью поражения почек и уровнем увеличения циркулирующих активированных субпопуляций Т-лимфоцитов, проявляющих цитотоксическую активность

Keywords

мезангиопролиферативный гломерулонефрит, нефротический синдром, нефробиопсия, иммунофенотипирование, субпопуляции лимфоцитов периферической крови

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
gold