
Analyzed were the quantitative and functional characteristics of circulating lymphocytes subpopulations and their relationship with other indicators of severity of mesangioproliferative glomerulonephritis in 43 patients. Established was the dependence between the severity of the process and the activation of lymphoid populations of peripheral blood lymphocytes, as well as a marked correlation between the severity of renal damage and increased levels of circulating activated subpopulations of T-lymphocytes, which exhibit cytotoxic activity.
Проанализированы количественные и функциональные особенности субпопуляций циркулирующих лимфоцитов и их связи с другими показателями тяжести мезангиопролиферативного гломерулонефрита у 43 пациентов. Выявлены зависимость между тяжестью процесса и активацией лимфоидных популяций лимфоцитов периферической крови, а также выраженная корреляция между тяжестью поражения почек и уровнем увеличения циркулирующих активированных субпопуляций Т-лимфоцитов, проявляющих цитотоксическую активность
мезангиопролиферативный гломерулонефрит, нефротический синдром, нефробиопсия, иммунофенотипирование, субпопуляции лимфоцитов периферической крови
мезангиопролиферативный гломерулонефрит, нефротический синдром, нефробиопсия, иммунофенотипирование, субпопуляции лимфоцитов периферической крови
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