
Представлен обзор литературы по остаточным эффектам миоплегии после операций. Обоснована необходимость применения мониторинга нервно-мышечной проводимости при нейрохирургических операциях с учетом вариабельности действия миорелаксантов и неврологического дефицита, наблюдаемого у больных данной категории. Проведен анализ побочных эффектов ингибиторов ацетилхолинэстеразы, и доказана необходимость применения избирательных антагонистов нейромышечных блокаторов, способных связывать активные молекулы миорелаксанта в организме без специфического воздействия на холинергические рецепторы.
Presented was a review of literature on the residual effects of myoplegia after surgery. Justified was the necessity of monitoring neuromuscular conduction during neurosurgical operations, taking into account the variability of muscle relaxants and neurological deficits observed in patients of this category. Conducted was an analysis of adverse effects of acetylcholinesterase inhibitors, and proven was the need for electoral antagonists of neuromuscular blockers that can bind active molecules of the muscle relaxant in the body without specific effects on cholinergic receptors
нервно-мышечная проводимость, миоплегия, миорелаксанты
нервно-мышечная проводимость, миоплегия, миорелаксанты
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