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Клинико-биохимические аспекты эндокринно-метаболического стресс-ответа и нарушений системы гемостаза при операциях на позвоночнике высокой интенсивности

Клинико-биохимические аспекты эндокринно-метаболического стресс-ответа и нарушений системы гемостаза при операциях на позвоночнике высокой интенсивности

Abstract

Цель исследования: диагностика и оценка влияния методов анестезии на эндокринно-метаболический ответ и систему гемостаза/фибринолиза при операциях на позвоночнике высокой интенсивности. В исследование вошли 165 пациентов. Выделены 2 группы больных: в первой группе применяли грудную эпидуральную анальгезию и общую анестезию, во второй – общую анестезию. Выявлено, что эпидуральная анальгезия обеспечивает наиболее адекватную антиноцицептивную защиту организма во время и после операций в вертеброхирургии. Использование эпидуральной анальгезии способствует сдерживанию хирургического стресс-ответа при операциях на позвоночнике и спинном мозге, в том числе ограничивает активацию системы гемостаза/фибринолиза.

Objective: diagnosis and evaluation of the influence of methods of anesthesia on the endocrine-metabolic response and the system of hemostasis/fibrinolysis during spine surgery operations of high intensity. The study included 165 patients. All patients were divided into two groups. Thoracic epidural analgesia and general anesthesia were using in the first group and only general anesthesia – in the second group. The results showed that thoracic epidural analgesia provided the most adequate analgesic protection during and after spine surgery. The use of epidural analgesia contributes to limiting the surgical stress-response and level changes in hemostasis/fibrinolysis during these operations.

Keywords

ВЕРТЕБРОХИРУРГИЯ, ГРУДНАЯ ЭПИДУРАЛЬНАЯ АНАЛЬГЕЗИЯ, ХИРУРГИЧЕСКИЙ СТРЕСС-ОТВЕТ, ГЕМОСТАЗ, ФИБРИНОЛИЗ

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
gold