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Функциональное состояние эндотелия и течение ишемической болезни сердца после интервенционного вмешательства

Функциональное состояние эндотелия и течение ишемической болезни сердца после интервенционного вмешательства

Abstract

In order to evaluate the infl uence of endothelial dysfunction on the longterm prognosis after surgical interventions (SI) in patients with heart ischemic disease in combination with arterial hypertension the authors examined 74 patients who were operated 5-8 years ago. The content of nitrates, arginine and desquamative endotheliocytes (DE) or nitrites, citrulline and DE in plasma were combined into integral index of endothelial dysfunction. Trustworthy more expressed endothelial dysfunction was revealed in patients with poor prognosis just after SI and in 5-8 years after SI in comparison with such dysfunction in patients with favourable prognosis.

Для оценки влияния эндотелиальной дисфункции на отдаленный прогноз после интервенцион- ных вмешательств (ИВ) у пациентов с ишемической болезнью сердца в сочетании с артериальной гипер- тонией обследованы 74 пациента, перенесших ИВ 5-8 лет назад. Содержание нитратов, аргинина и десква- мированных эндотелиоцитов (ДЭ) или нитритов, цитруллина и ДЭ в плазме объединили в интегральный показатель эндотелиальной дисфункции. У пациентов с неблагоприятным прогнозом исходно и через 5-8 лет после ИВ выявлена достоверно более выраженная эндотелиальная дисфункция по сравнению с тако- вой у лиц с благоприятным прогнозом.

Keywords

ИШЕМИЧЕСКАЯ БОЛЕЗНЬ СЕРДЦА, АРТЕРИАЛЬНАЯ ГИПЕРТОНИЯ, ЭНДОТЕЛИАЛЬНАЯ ДИСФУНКЦИЯ, АНГИОПЛАСТИКА И СТЕНТИРОВАНИЕ КОРОНАРНЫХ АРТЕРИЙ

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
gold