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Фармакотерапия ожирения: прошлое, настоящее и будущее

Фармакотерапия ожирения: прошлое, настоящее и будущее

Abstract

В обзоре описана эволюция фармакотерапии ожирения начиная от применения растительных средств, тиреоидных гормонов и симпатомиметиков, и заканчивая серотонинергическими препаратами, ингибиторами липазы, аналогами пептидов и комбинированными средствами. Описаны препараты, утвержденные в настоящее время для длительного лечения ожирения, такие как орлистат, лоркасерин, лираглутид, и комбинации фентермин/ топирамат и налтрексон/бупропион. Сделан вывод, что наиболее перспективными препаратами для лечения ожирения в будущем будут комбинации препаратов с различными механизмами действия.

Keywords

ОЖИРЕНИЕ,ЛЕЧЕНИЕ,ФАРМАКОТЕРАПИЯ

  • BIP!
    Impact byBIP!
    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    0
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Average
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Average
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Average
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
gold