Powered by OpenAIRE graph
Found an issue? Give us feedback
image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Bulletin of Orenburg...arrow_drop_down
image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
addClaim

This Research product is the result of merged Research products in OpenAIRE.

You have already added 0 works in your ORCID record related to the merged Research product.

Сравнительный анализ слоя фоторецепторов у пациентов с субретинальной неоваскуляризацией после фотодинамической терапии и анти-VEGF-терапии

Сравнительный анализ слоя фоторецепторов у пациентов с субретинальной неоваскуляризацией после фотодинамической терапии и анти-VEGF-терапии

Abstract

This article describes the problems in the treatment of subretinal neovascularization. A comparative analysis of the photoreceptor layer thickness in patients with subretinal neovascularization after photodynamic therapy and anti-VEGF-therapy for age-related macular degeneration.Subretinal neovascularization is one of the leading reasons for the decline of central vision in the age group of patients older than 50 years. With the introduction of the treatment of this group of patients photodynamic therapy and anti-VEGF-therapy there was a significant improvement in treatment outcomes.Since November 2002, in the laser department of the Samara Regional Clinical Hospital named after ophthalmic T.I. Eroshevsky performed PDT using the photosensitizer Vizudin (firm Novartis Ophthalmics) and laser photoactivators OPAL (firm Lumenis).). Since 2009, the practice GBUZ SOKOB by T.I. Eroshevsky technique has been introduced anti-VEGF therapy with Lucentis. During this time held in 1536 intravitreal injections of Lucentis (IVVL) in 591 patients with age-related macular degeneration (AMD). This treatment was carried out in the framework of the Programme,developed by the Ministry of Health and Social Development of the Samara region «in order to implement the activities of the priority national project in the field of health care, improve the quality and availability of high-tech medical aid to the population of the Russian Federation.» There were analyzed 31 patients with subretinal neovascularization developed against age-related macular degeneration after photodynamic therapy and anti-VEGF-therapy. Of these patients after PDT, 16 (9 patients after PDT, patients after PDT combined with corticosteroids 7), 15 patients after IVVL photoreceptor layer measurement was carried out at a distance of 500 to1000 m from the edge of the subretinal membrane optical coherence tomography RTVue.

В данной статье рассмотрены проблемы лечения субретинальной неоваскуляризации. Проведен сравнительный анализ толщины слоя фоторецепторов у пациентов с субретинальной неоваску-ляризацией после фотодинамической терапии и анти-VEGF-терапии при возрастной макулодист-рофии. Субретинальная неоваскуляризация является одной из ведущих причин снижения центрального зрения в возрастной группе пациентов старше 50 лет. После введения в практику лечения данной группы больных фотодинамической терапии и анти-VEGF-терапии произошло значительное улучшение исходов лечения. С ноября 2002 года в лазерном отделении Самарской областной клинической офтальмологической больницы имени Т.И. Ерошевского выполнялась ФДТ с применением фотосенсибилизатора Визудин (фирма Novartis Ophthalmics) и лазерного фотоактиватора OPAL (фирма Lumenis). С 2009 года в практику ГБУЗ СОКОБ им. Т.И. Ерошевского внедрена методика анти-VEGF терапии с использованием препарата Луцентис. За это время проведено 1536 интравит-реальных инъекций Луцентиса (ИВВЛ) у 591 пациента с возрастной макулодистрофией (ВМД). Данное лечение проводилось в рамках Программы, разработанной Министерством здравоохранения и социального развития Самарской области «в целях реализации мероприятий приоритетного национального проекта в сфере здравоохранения, повышения качества и доступности высокотехнологичной медицинской помощи населению Российской федерации». Проанализирован 31 пациент с субретинальной неоваскуляризацией, развившейся на фоне возрастной макулодистрофии после фотодинамической терапии и анти-VEGF-терапии. Из них пациентов после ФДТ 16 (пациентов после ФДТ 9, пациентов после ФДТ, комбинированной с кортикостероидами 7), пациентов после ИВВЛ 15. Измерение слоя фоторецепторов проводилось на расстоянии 500-1000 мкм от края субретинальной мембраны на оптическом когерентном томографе RTVue.

Keywords

ВИЗУДИН, СУБРЕТИНАЛЬНАЯ НЕОВАСКУЛЯРИЗАЦИЯ, ФОТОДИНАМИЧЕСКАЯ ТЕРАПИЯ, АНТИ-VEGF-ТЕРАПИЯ

  • BIP!
    Impact byBIP!
    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    0
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Average
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Average
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Average
Powered by OpenAIRE graph
Found an issue? Give us feedback
selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
gold
Related to Research communities